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. 2014 Apr 19;3:262–272. doi: 10.1016/j.euprot.2014.04.002

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© 2014 The Authors

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/3.0/).

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Fig. 3 — Maximum-likelihood phylogeny of orphan and deorphanised C. elegans neuropeptide GPCRs.

The phylogeny reveals 27 putative FLP-GPCRs which clustered with deorphanised C. elegans FLP-receptors. C. elegans neuropeptide GPCR entries are identified as per previous designation [28] or NCBI accession number. Deorphanised C. elegans FLP-GPCRs are highlighted by an asterix. FLP-GPCR cluster nodes supported by a bootstrap analysis value of >70% are identified by red dots. Clusters are highlighted in blue (1), pink (2) or yellow (3) shading. Bootstrap values are shown as percentages.