Table 1.
Clinical and echocardiographic characteristics of study subjects
| Characteristic | Nonischemic HF (n = 11) | Ischemic HF (n = 11) |
|---|---|---|
| Clinical | ||
| Age, years | 49 ± 14 | 54 ± 9 |
| Sex (M/F) | 7/4 | 9/2 |
| No. of subjects with diabetes | 5 | 8 |
| Serum creatinine level, mg/dL | 1.6 ± 0.7 | 1.6 ± 0.7 |
| Hematocrit, % | 34 ± 5 | 35 ± 6 |
| Therapy, no. of subjects | ||
| ACEI/ARB | 7 | 7 |
| Beta-blocker | 10 | 9 |
| Aldosterone inhibitor | 9 | 9 |
| PDE V inhibitor | 4 | 1 |
| Inotropic therapy | 10 | 10 |
| Intra-aortic balloon pump* | 0 | 5 |
| Ventricular assist device | 1 | 0 |
| Hemodynamic | ||
| Right atrial pressure, mmHg | 9 ± 6 | 8 ± 6 |
| Mean pulmonary artery pressure, mmHg | 26 ± 8 | 27 ± 10 |
| Pulmonary capillary wedge pressure, mmHg | 16 ± 8 | 17 ± 7 |
| Pulmonary vascular resistance, Woods units | 2.2 ± 0.6 | 2.6 ± 1.7 |
| Cardiac index, L/min/m2 | 2.2 ± 0.4 | 2.1 ± 0.4 |
| Echocardiographic | ||
| RV basal, cm | 4.6 ± 0.5 | 4.5 ± 0.8 |
| RV long axis, cm | 8.3 ± 1.1 | 7.3 ± 0.6 |
| TAPSE, mm | 14.3 ± 4.9 | 11.7 ± 3.9 |
| RIMP | 54.7 ± 25.6 | 49.6 ± 10.7 |
| FAC, % | 29.2 ± 20.7 | 33.2 ± 11.4 |
| RAP, estimated mmHg | 8.7 ± 4.7 | 6.3 ± 5.1 |
| Moderate or severe dysfunction, no. of subjects | 5 | 6 |
Note
Data are mean value ± standard deviation, unless otherwise indicated. Asterisk indicates P < 0.05. ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker; FAC: right ventricular fractional area change; HF: heart failure; PDE V: phosphodiesterase type V; RAP, right atrial pressure; RIMP: RV index of myocardial performance; RV: right ventricular; TAPSE: tricuspid annular plane systolic excursion.