A, percentage vasodilatation to MCh in mesenteric arteries from males (n = 7–13). Responses to methylcholine in control and IUGR animals in sedentary or exercised groups are shown in the absence of inhibitors (open circles), in the presence of l-NAME (filled circles), or in the presence of MnTBAP (open triangles). B, summary data of the ΔAUC in vessels incubated with no inhibitor or l-NAME, equivalent to the contribution of NO to the vasodilator response to MCh, and in vessels incubated with no inhibitor or MnTBAP, equivalent to the contribution of ROS to the vasodilator response to MCh. Data are presented as mean ± SEM.