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The accumulation of advanced glycation end-products (AGEs) was fluorimetrically quantified in the cortex of the femora in unirradiated and 70 kGy irradiated human cortical bone samples. AGEs increase slightly when bone is irradiated with a dose of 70 kGy which increased the concentration of fluorescent (non-enzymatic) cross-links to ~21% more than in the unirradiated bone.
