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. Author manuscript; available in PMC: 2016 Mar 1.
Published in final edited form as: Circ Heart Fail. 2015 Feb 10;8(2):362–372. doi: 10.1161/CIRCHEARTFAILURE.114.001274

Figure 3. Development of cardiac remodeling in aged sFRP-1 KO mice.

Figure 3

(A) Representative hematoxylin and eosin (H&E) staining of the sFRP-1 WT and sFRP-1 KO hearts at one year of age. Scale bars represent the length of 2mm. (B-D) Echocardiographic analysis of the sFRP-1 WT and KO mice hearts representing (WT/n=3; KO/n=7); (B) LV end diastolic dimension (LVEDD- [cm]) (C) LV posterior wall thickness (PW-[cm]) (D) Fractional Shortening, (FS-[%)]. Significant differences were denoted by *P < 0.05 < or **P < 0.01, or ***P < 0.001. > vs control littermate hearts. All values were expressed as mean ± SEM