Table 2.
Baseline | 4 weeks | 8 weeks | P-value | |
---|---|---|---|---|
Menopausal symptom score | ||||
MSS score | 9.9 (5.2) | 8.5 (5.0)** | 8.3 (5.0)*** | <0.0001a |
HADS-anxiety subscale score | 5.3 (2.7) | 4.8 (2.4)# | 4.9 (2.9)# | 0.04b |
HADS-depression subscale score | 4.7 (3.2) | 4.6 (3.4) | 4.4 (3.3) | 0.32b |
Athens Insomnia Scale score | 3.7 (2.3) | 3.4 (2.4) | 3.8 (2.8) | 0.16b |
Body composition | ||||
Height, cm | 157.5 (4.9) | 157.5 (4.9) | 157.5 (4.9) | 0.50b |
Weight, kg | 55.0 (8.5) | 54.9 (8.6) | 55.0 (8.6) | 0.13a |
Body mass index, kg/m2 | 22.2 (3.2) | 22.1 (3.2) | 22.2 (3.2) | 0.34a |
Fat mass, kg | 15.7 (6.1) | 15.8 (6.2) | 15.7 (6.2) | 0.58b |
Muscle mass, kg | 37.0 (3.1) | 36.9 (3.0) | 37.1 (3.0) | 0.046a |
Blood pressure and heart rate | ||||
Systolic blood pressure, mmHg | 116.9 (14.1) | 117.8 (14.3) | 117.0 (13.8) | 0.87b |
Diastolic blood pressure, mmHg | 75.4 (10.4) | 75.2 (9.7) | 74.5 (9.3) | 0.23b |
Heart rate, min−1 | 62.6 (9.4) | 64.4 (8.6)## | 63.8 (8.2)## | 0.03b |
Resting Energy Expenditure | 1980 (368) | 2108 (440)** | 2149 (470)** | 0.003a |
Blood examination | ||||
Triglycerides, mg/dL | 115.9 (84.0) | 116.3 (70.2) | 107.4 (75.3) | 0.25b |
Total cholesterol, mg/dL | 213.1 (33.4) | 213.9 (36.1) | 212.2 (36.8) | 0.76a |
LDL cholesterol, mg/dL | 120.3 (28.8) | 121.1 (31.2) | 120.2 (32.2) | 0.87a |
HDL cholesterol, mg/dL | 73.2 (16.3) | 75.3 (14.9) | 74.6 (15.0) | 0.31a |
Glucose, mg/dL | 98.9 (16.6) | 98.8 (11.6) | 99.2 (19.0) | 0.51b |
HbA1c, % | 5.3 (0.4) | 5.3 (0.4) | 5.4 (0.4) | 0.36b |
Data are shown as means (standard deviations).
aOne-way repeated measures analysis of variance.
bFriedman test.
**P < 0.01, ***P < 0.001 versus baseline, Paired t-test.
#P < 0.05, ##P < 0.01 versus baseline, Wilcoxon signed-rank test.