Figure 5.

Mgp Cre–mediated lacZ expression in the sclera. Five-μm meridional section from representative Mgp^Cre/+; R26R^lacZ/+ 4.5-week-old mouse stained as a whole globe with X-gal, embedded in paraffin and counterstained with hematoxylin and eosin. Expression of lacZ is not observed at the anterior sclera. It is beginning to show at the mid sclera and is highly expressed at the ppSC region. In the mid sclera, expression is mostly seen in the cell layer immediately underneath the choroid (chondrocyte layer).