Skip to main content
. 2015 Apr 10;56(4):2203–2214. doi: 10.1167/iovs.15-16460

Figure 7.

Figure 7

Mgp Cre–mediated lacZ expression with age. Five-μm meridional sections from representative X-gal–stained eyes from 2.5- to 8-months old and counterstained with hematoxylin and eosin. Top row: TM region; bottom row: ONH region. The 2.5-month-old mouse images (TM and ONH) were from littermates, stained as bisected tissues and embedded in paraffin. The TMs and ONHs images of the 4- and 6-month-old mice were each from the same eye. The 4- and 6-month-old mice were from different breeding pairs, stained as whole globes, and embedded in Technovit resin. The 8-month-old mouse images are also from the same eye, stained as bisected tissues and embedded in paraffin. The 2.5- and 6 month-old mice are from the same litter. Expression of lacZ is very high up to 6 months of age and begins to diminish at 8 months, last time point tried. Original magnifications: Top row: ×400; bottom row: ×200.