TABLE 1.
Comparison of IFN-γ responses by PBMC from M. bovis-infected cattle to responses by cattle naturally sensitized to M. avium
| Group | IFN-γ responsea to recall antigen:
|
||
|---|---|---|---|
| PPDa | PPDb | rESAT-6:CFP-10 | |
| M. bovis-infected (6 mo postinfection) | 17.3b (3.0) | 55.2c (9.7) | 29.1c (6.1) |
| M. avium-exposed (natural exposure) | 7.5 (3.0) | −2.4 (1.1) | −2.9 (0.7) |
a
Values are the mean IFN-γ responses (in nanograms per milliliter) (n = 8) of PBMC to antigen stimulation minus their response to medium alone after 48 h. Values in parentheses are the standard errors of the means.
b
Significantly different from the response by M. avium-exposed cattle (P < 0.05).
c
Significantly different from the response by M. avium-exposed cattle (P < 0.01).