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. 2004 Jul;11(4):651–657. doi: 10.1128/CDLI.11.4.651-657.2004

TABLE 1.

Comparison of EIAs for the detection of WNV IgM antibodies in the serum of experimentally infected monkeysa

Monkey Day monkey was identified as WNV IgM positive by:
COS-1 cell-based assay
S2 cell-based assay
First Last First Last
J840 12 28 13b 21
R470 11 45 11 45
T810 10c 63 10 63
P469 9 63 9 63
P659 9 45 10 28
a

Serum samples were collected on days 0, 1 to 14, 21, 28, 45, and 63 postinfection. All animals were euthanized on day 63 postinfection except for monkey R470, which was euthanized on day 45.

b

For monkey J840, the S/N ratio as determined by the S2 assay for the sample obtained on day 12 was 4.10, and the cutoff S/N ratio was 4.20.

c

For monkey T810, the sample obtained on day 12 was WNV RNA positive as determined by reverse transcription-PCR (15).