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. 2015 Apr 22;5:94. doi: 10.3389/fonc.2015.00094

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Copyright © 2015 Bauer, Takacs, Slotta-Huspenina, Langer, Becker, Novotny, Ott, Walch, Hapfelmeier and Keller.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Staining patterns for NOTCH1 (A–D) and NOTCH2 (E–H) in primary resected GC specimen. NOTCH1: (A) high-intensity cytoplasmic staining (SI 12), (B) medium-intensity cytoplasmic staining (SI 4), (C) low-intensity cytoplasmic staining (SI 2), and (D) negative cytoplasmic staining for NOTCH1 (SI 0); NOTCH2: (E) high-intensity cytoplasmic staining (SI 9) and low-intensity nuclear staining (SI 1), (F) medium-intensity cytoplasmic staining (SI 6) and low-intensity nuclear staining (SI 1); (G) low-intensity cytoplasmic staining (SI 3) and negative nuclear staining (SI 0); and (H) negative cytoplasmic and nuclear staining for NOTCH2. Scale bars: 50 μm.