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. 2015 Apr 22;9:140. doi: 10.3389/fnins.2015.00140

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Copyright © 2015 Weth, Benetti, Rauch, Gstraunthaler, Schmidt, Geisslinger, Sabbadini, Proia and Kress.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Thermal hypersensitivity after injection of activated platelets not mediated through the S1P₁ receptor. After intracutaneous injection of platelet preparations (10 μl; 10⁷ platelets/μl) no differences in PWL reduction were detected between SNS-S1P₁^−/− and S1P^fl/fl control mice (Two-Way Repeated Measures ANOVA: n.s.).