Table 1.
Patient Demographics
Characteristic | No (%) |
---|---|
No. of patients | 11 (100) |
Age, years | |
Median (Range) | 53 (36–68) |
Race / ethnicity | |
White | 6 (54.5) |
Black | 3 (27.3) |
Asian | 1 (9) |
Hispanic | 1 (9) |
Stage of disease | |
Metastatic | 11 (100) |
Visceral only | 3 (27.3) |
Visceral and nonvisceral | 3 (27.3) |
Nonvisceral only | 5 (45.4) |
Hormone receptor status | |
ER, PR or both positive | 3 (27.3) |
ER and PR negative | 8 (72.7) |
HER2 positive (IHC combined with FISH) | 11 (100) |
Previous therapy | |
Anthracyclines | 9 (81.8) |
Taxanes | 10 (91) |
Trastuzumab as adjuvant therapy | 4 (36.4) |
Trastuzumab for metastatic disease | 11 (100) |
Cumulative duration of prior trastuzumab (wk) | |
Median (Range) | 82 (22–136) |
Time from last cycle trastuzumab to initiation of trastuzumab and pertuzumab (wk) | |
Median (Range) | 13 (4–96) |
Abbreviations: ER, estrogen receptor; PR, progestin receptor; IHC, immunohistochemistry; FISH, fluorecsence in-situ hybridization; wk, week.