Table 1.
Patient Demographics
| Characteristic | No (%) |
|---|---|
| No. of patients | 11 (100) |
| Age, years | |
| Median (Range) | 53 (36–68) |
| Race / ethnicity | |
| White | 6 (54.5) |
| Black | 3 (27.3) |
| Asian | 1 (9) |
| Hispanic | 1 (9) |
| Stage of disease | |
| Metastatic | 11 (100) |
| Visceral only | 3 (27.3) |
| Visceral and nonvisceral | 3 (27.3) |
| Nonvisceral only | 5 (45.4) |
| Hormone receptor status | |
| ER, PR or both positive | 3 (27.3) |
| ER and PR negative | 8 (72.7) |
| HER2 positive (IHC combined with FISH) | 11 (100) |
| Previous therapy | |
| Anthracyclines | 9 (81.8) |
| Taxanes | 10 (91) |
| Trastuzumab as adjuvant therapy | 4 (36.4) |
| Trastuzumab for metastatic disease | 11 (100) |
| Cumulative duration of prior trastuzumab (wk) | |
| Median (Range) | 82 (22–136) |
| Time from last cycle trastuzumab to initiation of trastuzumab and pertuzumab (wk) | |
| Median (Range) | 13 (4–96) |
Abbreviations: ER, estrogen receptor; PR, progestin receptor; IHC, immunohistochemistry; FISH, fluorecsence in-situ hybridization; wk, week.