. Author manuscript; available in PMC: 2015 Apr 22.

Published in final edited form as: Clin Cancer Res. 2008 May 1;14(9):2710–2716. doi: 10.1158/1078-0432.CCR-07-4636

Table 2.

Observed toxicity events for patients receiving trastuzumab plus pertuzumab

	CTC Grade
	1		2		3		4
Toxicity	N	%	N	%	N	%	N	%

Hematologic
Neutropenia	0	0	0	0	0	0	0	0
Hemoglobin	2	18	0	0	0	0	0	0
Thrombocytopenia	2	18	0	0	0	0	0	0
Nonhematologic
Diarrhea	2	18	3	27	0	0	0	0
Allergic reaction	2	18	0	0	1	9	0	0
Rash	1	9	0	0	0	0	0	0
Nail changes	2	18	1	9	0	0	0	0
Left ventricular systolic Dysfunction	3	27	2	18	1	9	0	0

N: number of patients.