TABLE 1.
ELISA detection of a 58-kDa HpCA in 221 serum samples of individuals who were confirmed by culture to be infected or not infected with H. pylori
| Result of microbiological culture of gastric biopsy specimena | No. of samples | No. of samples with indicated HpCA ELISA resultb
|
% Positive | |
|---|---|---|---|---|
| Positive | Negative | |||
| Positive | 144 | 133 (TP) | 11 (FN) | 92 |
| Negative | 77 | 7 (FP) | 70 (TN) | 9 |
a
The gold standard for the diagnosis of H. pylori infection.
b
TP, true-positive result; FP, false-positive result; TN, true-negative result; FN, false-negative result. Percent sensitivity = TP/(TP + FN) = 133/(133 + 11) × 100 = 92%; percent specificity = TN/(TN + FP) = 70/(70 + 7) × 100 = 91%; positive predictive value (percentage) = TP/(TP + FP) = 133/(133 + 7) × 100 = 95%; negative predictive value (percentage) = TN/(TN + FN) = 70/(70 + 11) × 100 = 86%; efficiency of the test (percentage) = (TP + TN)/total = (133 + 70)/221 × 100 = 92%.