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. 2015 Apr 18;14:31. doi: 10.1186/s12944-015-0030-5

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© Ning et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Effects of 1,25 (OH) ₂D₃ on the expression of hepatic NF-κ B and the related genes. The mRNA expression of hepatic NF-κ B and related genes were assessed. The relative mRNA levels were determined by quantitative RT-PCR and normalized to β-actin. Each gene expression was determined by the 2-ΔΔCt method. (A) The mRNA level of hepatic NF-κ B. (B) The mRNA level of MCP-1, (C) The mRNA level of hepatic ICAM-1, (D) The mRNA level of hepatic TGF-β1. Data are expressed as mean ± SD of each group (n = 15 per group). NC, normal control group; DM, diabetic group; VD, vitamin D treatment group. *P < 0 .05 vs. NC; #P < 0 .05 vs. DM.