TABLE 1.
Demographics and Outcomes Among Three Patient Groups
| Variable | At Risk | ARDS Utah | ARDS ARDSNet | p value* |
|---|---|---|---|---|
| APACHE III at enrollment (points) | 70.56 | 83.14 | 92.28 | <0.001 |
| PF Ratio at enrollment | 207.1 | 130.71 | 135.28 | <0.001 |
| Age (years) | 52.85 | 52.39 | 50.88 | <0.001 |
| Female sex (percent) | 51% | 56% | 47% | 0.59 |
| 28-day mortality (percent) | 4% | 14% | 18% | <0.001 |
| Risk factor | ||||
| Trauma | 14% | 6% | 8% | 0.03 |
| Sepsis | 58% | 21% | 24% | <0.001 |
| Transfusion | 3% | 4% | 2% | 0.38 |
| Aspiration | 2% | 14% | 18% | <0.001 |
| Pneumonia | 19% | 49% | 41% | <0.001 |
| Ventilator-free days | 25.57 | 17.44 | 15.21 | <0.001 |
| ICU-free days | 17.5 | 11.92 | 14.21 | <0.001 |
| Organ-failure free days | 27.29 | 26.25 | 10.93 | <0.001 |
ARDS = Acute Respiratory Distress Syndrome; ARDSNet = National Institutes of Health ARDS Clinical Trials Network.
*
For comparison of all ARDS vs. all at risk patients.