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. Author manuscript; available in PMC: 2015 Sep 1.
Published in final edited form as: Mol Phylogenet Evol. 2014 May 23;78:172–184. doi: 10.1016/j.ympev.2014.05.013

Figure 2.

Figure 2

The PvMSP3 and PfMSP3 families are not syntenic among Plasmodium species. Chromosomes and position of the gene arrays are drawn approximately to scale; centromeres are arbitrarily placed in the middle of chromosomes. Homologous synteny blocks are colored the same on the chromosomes, such that for example, the region syntenic to P. vivax chromosome 14 (purple) in the P. falciparum genome (in this case, on P. falciparum chromosome 12) is colored similarly (see Frech and Chen (2011) for more about synteny blocks). P. falciparum surface proteins clustering with PfMSP3 (PfMSP3.1) in the PfMSP3 array (orange) include MSP6 (PfMSP3.2), MSP-H101 (PfMSP3.3), Duffy Binding-Like MSP (PfMSP3.4), MSP11 (PfMSP3.7), and MSP/PF10_0355 (PfMSP3.8). Additional P. falciparum antigens not originally considered part of the Pf msp3 family are also present within the array, nluding S-antigen (PF3D7_1036400), liver stage antigen 1 (PF3D7_1036400), and GLURP (PF3D7_1036400).