Figure 5.
Bayesian phylogeny of the msp3 gene family of P. vivax and its closely related species. Nodes with greater than 50% posterior probability support from 55 × 106 MCMC generations are shown. Nodes with ML support based on a bootstrap with 100 pseudoreplications are indicated as * for 95–100%, nodes with less than 80% are not indicated. Branches are colored by species and clades are labeled by the gene from the Pvmsp3 array (shown below the phylogeny) they contain. A reduced set of 4 P. vivax, 4 P. cynomolgi, and 3 P. inui isolates for each gene was used for the unrooted phylogeny. Two P. cynomolgi genes, msp3F2 and msp3F3, which appeared to be recombinants of msp3F and msp3D (see results), were excluded in this tree. A Bayesian tree including these two genes is shown in the supplementary information (Supplementary Figure 4).