Table 1.

Association of rs10816625, rs13294895 and rs676256 with risk of breast cancer amongst women of European and Asian ancestry

Locus	Population	Control MAF	Control genotype counts			Case MAF	Case genotype counts			P-valuea	ORb	95% CIb
rs10816625			AA	AG	GG		AA	AG	GG
9q31.2	Caucasians	0.06	37579	4851	169	0.07	37 434	5560	164	7.89 × 10−09	1.12	1.08–1.17
110 837 073	Asians	0.38	2633	2976	1013	0.42	2023	2714	1057	2.77 × 10−05	1.12	1.06–1.18
rs13294895			GG	AG	AA		GG	AG	AA
9q31.2	Caucasians	0.20	28 954	12 372	1272	0.19	28 625	13 029	1506	2.97 × 10−11	1.09	1.06–1.12
110 837 176	Asians	0.03	6244	372	8	0.03	5495	288	10	0.66	1.04	0.89–1.21
rs676256			AA	AG	GG		AA	AG	GG
9q31.2	Caucasians	0.38	16166	20183	6250	0.36	18 011	19 670	5472	1.58 × 10−25	0.90	0.88–0.92
110 895 353	Asians	0.05	6036	567	21	0.04	5329	455	11	0.3	0.94	0.82–1.06

^aP-values from single SNP test of association, computed from a likelihood-ratio test with one degree-of-freedom.

^bOdds ratios and 95% confidence intervals for SNP association with breast cancer estimated using logistic regression, adjusting for study and significant principal components and assuming multiplicativity on the odds scale for heterozygote and minor-allele homozygote ORs.