Table 3.
Locus | Controls | Cases | ER/PR | ORa | 95% CI | P-valueb | Phetc |
---|---|---|---|---|---|---|---|
rs10816625 | 38 144 | 17 132 | ER+/PR+ | 1.17 | 1.11–1.24 | 4.76 × 10−09 | |
3380 | ER+/PR− | 1.06 | 0.96–1.18 | 0.27 | |||
714 | ER−/PR+ | 1.12 | 0.90–1.38 | 0.30 | |||
4436 | ER−/PR− | 1.07 | 0.98–1.18 | 0.12 | 0.03 | ||
rs13294895 | 38 143 | 17 132 | ER+/PR+ | 1.13 | 1.09–1.16 | 6.38 × 10−08 | |
3380 | ER+/PR− | 1.07 | 1.01–1.15 | 0.03 | |||
714 | ER−/PR+ | 1.00 | 0.87–1.15 | 0.97 | |||
4438 | ER−/PR− | 1.05 | 0.99–1.11 | 0.12 | 0.01 | ||
rs676256 | 38 144 | 17 128 | ER+/PR+ | 0.87 | 0.84–0.89 | 1.33 × 10−24 | |
3380 | ER+/PR− | 0.90 | 0.86–0.95 | 1.20 × 10−04 | |||
714 | ER−/PR+ | 0.89 | 0.80–1.00 | 0.04 | |||
4436 | ER−/PR− | 0.98 | 0.94–1.03 | 0.47 | 4.01 × 10−06 |
aStratum-specific ORs estimated using separate logistic regression models comparing cases from each ER/PR combination with all controls.
bStratum-specific P-values computed using Wald tests.
cP-value from χ2-test of heterogeneity of odds ratios.