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. Author manuscript; available in PMC: 2015 Apr 22.
Published in final edited form as: Hum Hered. 2013 Jul 31;76(1):28–35. doi: 10.1159/000353270

Figure 1.

Figure 1

Type 1 error rate for the CMC and burden tests uncorrected or corrected by principal component and genomic control for a 10kb region. 1-A: 500 cases and 500 controls collapsed by the CMC method; 1-B: 500 cases and 500 controls collapsed by the burden test; 1-C: 1000 case and 1000 control collapsed by the CMC method; 1-D: 1000 cases and 1000 controls collapsed by the burden test. Note that in all simulations, 50% of controls have African ancestry and 50% have European ancestry, while the proportion of cases with African ancestry varies across simulations (X-axis).