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. Author manuscript; available in PMC: 2015 Apr 22.
Published in final edited form as: J Neurogenet. 2014 Apr 22;28(0):98–111. doi: 10.3109/01677063.2014.892486

Figure 1.

Figure 1

Reduced locomotor activity and impaired motor coordination in PSD-95 deficient mice. (a) Time courses of horizontal activity per 5 min of WT, PSD-95+/-, and PSD-95-/- mice when placed in a novel environment, an open field activity chamber. (b) Summary of total horizontal and vertical activity of WT, PSD-95+/- and PSD-95-/- mice in response to a novel environment. **, p < 0.01, one-way ANOVA with post-hoc Dunnett's test vs. WT. (c) Total horizontal activity of WT, PSD-95+/-, and PSD-95-/-mice during a 5-day test period. Mice were placed in the same locomotor activity monitor on test days for 60 min. Horizontal and vertical activity was measured as distance traveled in blocks of 5 min. *, p < 0.05, one-way ANOVA with post-hoc Dunnett's test vs. corresponding WT controls. (d) Summary of beam walking data. Inset, a WT mouse performing the beam walking test. *, p < 0.05 versus WT, Student's t test. Numbers in parentheses designate numbers of mice used.