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. Author manuscript; available in PMC: 2015 Apr 22.
Published in final edited form as: J Neurogenet. 2014 Apr 22;28(0):98–111. doi: 10.3109/01677063.2014.892486

Figure 2.

Figure 2

Progressive limb-clasping symptoms in PSD-95 deficient mice. (a) Examples of hind-limb, all-limb and full body clasping in PSD-95-/- mice compared to a WT control. (b) Clasping duration in a 15-s interval. **, p < 0.01; ***, p≪0.001, Student's t-tests. A clasping event is defined by the retraction of limbs into the body and toward the midline. (c) Developmental progression of clasping phenotype. **, p < 0.01; ***, p≪0.001, one-way ANOVA followed by post hoc Newman–Keuls tests. Mice were observed during a 15 s tail suspension test to monitor the progression of the clasping phenotype between 4 and 20 weeks of age. Numbers in parentheses designate numbers of mice used.