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. 2015 Apr 22;10(4):e0124496. doi: 10.1371/journal.pone.0124496

Fig 8. Interplay between DOPA and copper in cell survival.

Fig 8

J774 cells were first treated with 100μM DOPA for 6 hours (black bars) or with vehicle (white bars). Copper oxide nanoparticles or copper ion or titanium dioxide nanoparticles were then added at the indicated concentrations for the remaining 18 hours prior to viability measurement. Hatched bar: cells treated with 100μM oxidized DOPA. Grey bar cells treated with PVP only (4μg/ml). Experiments were carried out in quadruplicate. Statistical confidence (Student T-test) is indicated as follows: *: p ≤ 0.05; ** p ≤ 0.01; *** p≤ 0.0011.