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. 2015 Apr 22;10(4):e0124496. doi: 10.1371/journal.pone.0124496

Table 3. Differentially-expressed proteins identified in the proteomic screen.

Spot Protein name Access Nb. Sequence TiO2/ctrl CuO/ctrl Cu ion/ctrl
Nb. Number peptide Cov. in % (fold/Ttest) (fold/Ttest) (fold/Ttest)
P: Protein production and folding
P1 eIF3j Q66JS6 2 10 0.84/0.81 0.46/0.025 0.79/0.64
P2 Elongation factor 1-delta P57776 2 13 1.04/0.91 0.7/0.04 1.05/0.34
M: Metabolism
M1 Aldose reductase P45376 4 13 0.995/0.96 0.53/0.02 0.92/0.52
M2 Glutamate DH 1 mitochondrial P26443 2 4 0.71/0.04 0.98/0.88 0.86/0.27
M3 DLAT, mitochondrial Q8BMF4 2 6 1.40/0.05 1.12/0.25 0.9/0.16
M4 Galactokinase Q9R0N0 3 8 1.005/0.97 0.32/0.001 1.005/0.97
S: Signalling
S1 Inositol monophosphatase 1 O55023 4 17 0.98/0.96 0.65/0.045 0.71/0.38
S2 Tumor protein D52 Q62393 3 17 0/97/0.68 0.38/0.001 0.83/0.07
S3 Guanine nucleotide-binding protein G P08752 4 13 0.97/0.85 0.6/0.03 1.02/0.92
O: Oxidative stress response
O1 Ferritin light chain 1 P29391 3 19 1.013/0.91 1.65/0.03 1.06/0.75
O2 Ferritin heavy chain P09528 3 19 2.95/0.35 1.76/0.35
O3 GSTomega-1 O09131 4 18 1.35/0.15 0.53/0.01 1.23/0.2
O4 Peroxiredoxin-6 O08709 6 33 1.17/0.48 0.83/0.01 1.2/0.23
O5 Glutamate—cysteine ligase reg. subunit O09172 3 14 0.95/0.83 1.735/0.02 1.22/0.24
O6 Heme oxygenase 1 P14901 3 17 1.02/0.95 6.37/0.05 0.82/0.54
D: Protein degradation
D1 Proteasome subunit beta type-9 P28076 2 10 0.66/0.39 0.45/0.01 1.02/0.91
D2 Ubiquitin C-terminal hydrolase L3 Q9JKB1 2 10 1.06/0.88 0.42/0.02 0.65/0.18
C: Cytoskeleton and trafic
C1a MAPREB1 (acidic spot) Q61166 3 17 a:0.78/0.08 a:0.3/0.001 a: 1.09/0.39
C1b MAPREB1 (basic spot) Q61166 4 16 b: 0.92/0.6 b:0.7/0.04 b: 1.03/0.7
C2 Charged MVB protein 4b Q9D8B3 4 17 1.04/0.85 0.7/0.04 0.85/0.5
C3 Tropomodulin-3 Q9JHJ0 3 10 0.75/0.12 0.54/0.025 1.23/0.03
C4 Stathmin P54227 6 39 0.83/0.68 0.49/0.04 0.66/0.27
C5 ARP 2/3 complex subunit 5 Q9CPW4 4 27 0.83/0.77 0.22/0.001 0.88/0.1
U: Miscellaneous
U1 Apoptosis-associated speck-like protein containing a CARD Q9EPB4 3 22 1.005/0.95 0.51/0.04 0.91/0.52
U2 Sepiapterin reductase Q64105 3 15 1.08/0.89 0.76/0.04 1.05/0.91
U3 Tumor protein D52 Q62393 3 17 0/97/0.68 0.38/0.001 0.83/0.07
U4 ATPase Asna1 O54984 3 11 1.58/0.04 0.68/0.123 0.99/0.96
U5 Proliferating cell nuclear antigen P17918 8 33 0.66/0.15 1.67/0.045 1.12/0.22