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. 2015 Apr 22;10(4):e0125641. doi: 10.1371/journal.pone.0125641

Fig 6. LNCaP microaggregates are more resistant to docetaxel compared to cells grown as monolayers.

Fig 6

LNCaP cells (50,000 cells/well) were treated with docetaxel over 48 hrs (A) or 72 hrs (B) at day 2 of growth either in 2D and 3D. Alamar blue was used to assess cell viability. Mean +/- SE, n = 4 biological replicates *P<0.05; the data shown is representative of three independent experiments. (C) Phase contrast images show the effects of docetaxel after 72 hrs on the morphology of the microaggregates (3D) compared to cells grown in monolayer (2D).