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. 2015 Apr 22;10(4):e0124325. doi: 10.1371/journal.pone.0124325

Fig 3. Activin A protects against 6-OHDA induced cell loss.

Fig 3

(A) Experimental timeline detailing pump implantation, unilateral injection of 6-OHDA or ascorbic acid (sham), and tissue collection. (B) Stereological quantification of TH-immunoreactive neurons in SNpc demonstrates activin A protects dopaminergic neurons against 6-OHDA toxicity. (C) Stereological quantification of NeuN-immunoreactive neurons in SNpc demonstrates activin A protects total neuron numbers against 6-OHDA induced toxicity. All values represent the mean ± standard error of the mean (SEM). *p<0.05, **p<0.01, ***p<0.001. Sham + vehicle n = 4, sham + activin A n = 6, 6-OHDA + vehicle n = 7, 6-OHDA + activin A n = 7.