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. 2015 Apr 22;10(4):e0123161. doi: 10.1371/journal.pone.0123161

Table 2. Baseline characteristics for the study participants in the ENRICA cohort study (2008–2010) according to categories of chocolate consumption.

Chocolate consumption (g/d)
Overall No consumption ≤ 10 g/day > 10 g/day p value
Participants (n) 4599 3327 479 793
Total chocolate consumption, g/day, mean (SD) 6.4 (19.8) 0 5.1 (2.5) 34.1 (36.5) <0.0001
Men, % 49.2 52.1 40.3 42.2 <0.0001
Age, mean (SD) 54.1 (17.2) 55.3 (17.9) 55.1(16.44) 51.1 (17.2) <0.0001
Educational level, %
    No formal or primary education 36.7 39.6 32.8 27.1 <0.0001
    Secondary education 36.4 34.8 38.0 41.9
    University 26.9 25.6 29.2 30.9
Tobacco consumption, %
    Never smokers 49.3 23.6 20.0 23.6 0.01
    Former smokers 27.4 28.3 23.6 26.0
    Current smokers 23.24 48.1 56.4 50.4
Alcohol consumption, g/day, mean (SD) 12.3 (20.1) 13.2 (21.0) 9.6 (16.1) 10.6 (10.5) <0.0001
Body mass index, Kg/m2, mean (SD) 27.4 (4.6) 27.6 (4.5) 27.0 (4.4) 26.9 (4.8) <0.0001
Abdominal obesity, % 42.8 43.9 38.8 40.7 <0.0001
Leisure time physical activity, METs h/week, mean (SD) 26.4 (20.4) 26.3 (20.3) 27.1 (21.4) 26.2 (20.0) 0.67
Time spent watching TV, (h/week), mean (SD) 15.0 (10.2) 15.2 (10.2) 15.0 (10.5) 14.8 (9.9) 0.55
Adherence to the Mediterranean diet, * %
    Low adherence (0–2 points) 15.7 16.3 11.7 22.6 <0,0001
    Medium adherence (3–5 points) 58.5 61.5 66.0 60.0
    High adherence (6–8 points) 25.7 22.2 22.3 18.0
Total energy intake, kcal/day, mean (SD) 2167 (624) 2101 (617) 2166 (525) 2446 (635) <0.0001
Prevalent diseases at baseline, %
    Coronary heart disease 0.8 0.9 0.6 0.4 0.20
    Stroke 0.6 0.6 0.6 0.5 0.94
    Cancer 1.2 1.4 0.6 0.8 0.10
    Depression 6.9 6.9 6.5 7.3 0.85
Incident diseases during follow-up, %
    Coronary heart disease 0.7 0.6 0.6 0.8 0.92
    Stroke 0.8 0.9 0.2 0.8 0.30
    Cancer 1.9 2.1 2.5 1.0 0.09
    Depression 6.8 6.8 6.5 7.1 0.92
Cardiovascular risk factors, %
Hypertension ** 44.0 45.8 39.6 39.1 0.0004
Diabetes 9.3 10.4 8.5 5.6 0.0002
Hypercholesterolemia 59.1 59.6 58.3 56.7 0.30
Physical component summary, mean (SD) 48.9 (10.8) 48.7 (10.9) 49.2 (9.6) 49.7 (10.2) 0.37
Mental component summary, mean (SD) 51.1 (10.2) 51.1 (10.4) 51.8 (9.1) 50.6 (9.8) 0.57
Physical component summary, mean (SD) 48.9 (9.4) 48.9 (9.5) 48.7 (9.5) 48.9 (9.7) 0.93
Mental component summary, mean (SD) 51.0 (9.5) 50.9 (9.6) 51.8 (9.5) 50.9 (9.7) 0.56

SD: Standard Deviation; MET: Metabolic Equivalents; TV: television;

* Trichopoulou score.

** Hypertension was defined as systolic pressure ≥140 mm Hg, diastolic pressure ≥90mmHg, or use of antihypertensive drugs.

†Diabetes mellitus was defined as serum glucose ≥126 mg/dl or use of antidiabetic drugs.

‡Hypercholesterolemia was defined as total serum cholesterol ≥200 mg/dl or use of hypolipidemic drugs.

║Adjusted for sex, age (18–44,45–64,65 and over), educational level (no formal or primary education; secondary education; university), tobacco consumption (never smokers, former smokers, current smokers), alcohol consumption g/day (quartiles), body mass index kg/m2 (quartiles), abdominal obesity (yes/no), leisure time physical activity METs-h/week (quartiles), time spent watching television h/week (quartiles), adherence to the Mediterranean diet (low adherence 0–2 points, medium adherence 3–5 points, high adherence 6–8 points), total energy kcal/day (quartiles) and prevalent diseases (coronary heart disease, stroke, cancer and depression).