Table 3.

Multivariable Cox regression for rectal cancer specific survival amongst pathologic node-negative patients treated with tri-modality therapy in California 2000–2007.

Characteristic		Neoadjuvant cohort N = 1916		Adjuvant cohort N = 658
		HR (95% CI)	p value	HR (95% CI)	p Value
Age (continuous – 10 year increment):		1.14 (1.00–1.29)	0.0468	1.22 (0.92–1.51)	0.0748
Sex:	Male	1.00 (reference)		1.00 (reference)
	Female	1.08 (0.79–1.49)	0.6288	1.02 (0.62–1.68)	0.4353
Race/Ethnicity:	Non-Hispanic White	1.00 (reference)		1.00 (reference)
	Non-Hispanic Black	1.39 (0.72–2.69)	0.3274	0.43 (0.10–1.80)	0.2467
	Hispanic	1.03 (0.66–1.59)	0.9074	0.78 (0.39–1.57)	0.4873
	Asian/Pacific Islander	0.96 (0.61–1.52)	0.8695	0.33 (0.12–0.93)	0.0364
Socioeconomic status:	1st – 2nd Quintile	1.00 (reference)		1.00 (reference)
	3rd Quintile	0.83 (0.55–1.26)	0.3776	2.04 (1.09–3.82)	0.0253
	4th – 5th Quintile	0.69 (0.47–1.00)	0.0498	1.14 (00.61–2.12)	0.6909
T stage:	0–1	1.00 (reference)		1.00 (reference)
	2	1.27 (0.65–2.45)	0.4835	2.03 (0.44–9.45)	0.3681
	3	1.76 (0.98–3.16)	0.0594	2.20 (0.53–9.19)	0.2806
	4	4.64 (2.47–8.74)	<0.0001	4.18 (0.90–19.34)	0.0672
Nodes examined:	0–2	1.38 (0.84–2.27)	0.2074	1.67 (0.67–4.20)	0.2723
	3–5	1.38 (0.88–2.17)	0.1638	3.02 (1.49–6.13)	0.0021
	6–8	1.20 (0.74–1.93)	0.4552	2.18 (1.08–4.40)	0.0301
	9–11	1.10 (0.64–1.87)	0.7390	1.84 (0.84–4.02)	0.1274
	12+	1.00 (reference)		1.00 (reference)