Table 1. Baseline patient characteristics.
Characteristic | All patients (N=282) |
---|---|
Median age in years (range) | 43 (20-75) |
20-29 | 33 (12%) |
30-39 | 72 (25%) |
40-49 | 97 (34%) |
50-59 | 58 (21%) |
60+ | 22 (8%) |
Ethnicity | |
Caucasian | 272 (96.5%) |
Other | 10 (3.5%) |
Menopausal status | |
Premenopausal | 199 (71%) |
Postmenopausal | 79 (28%) |
Primary reason for referral | |
FH of breast or ovarian cancer | 194 (69%) |
FH or personal history of a known genetic mutation | 20 (7%) |
Breast symptom | 19 (7%) |
Abnormal imaging | 17 (6%) |
LCIS or atypical hyperplasia | 30 (11%) |
Family history | |
Average number of affected members (range) | 2 (0-9) |
Mean age of the youngest relative with breast cancer (range) | 42 (19-80) |
Calculated lifetime risk of breast cancer of 20% or greater | 146 (51%) |
Personal history of a genetic mutation | 30 (11%) |
FH of a known genetic mutation | 39 (14%) |
FH= Family History; LCIS= Lobular Carcinoma In Situ.