Table 1.

Description of ALOX12, ALOX15, CRP, PTGIS, PTGS1, and PTGS2 polymorphisms, by ethnicity

Symbol	SNP ID	Chromosome Location	Coordinate	Region	Major/ Minor Allele1	non-Hispanic Whites			Hispanics			Proportion Missing
						Major allele freq.	Minor allele freq.	FDR adjusted HWE p value	Major allele freq.	Minor allele freq.	FDR adjusted HWE p value
ALOX12	rs9904779	17p13.1	6898615	INTERGENIC	G/C	0.63	0.37	0.98	0.68	0.32	0.73	0.0005
ALOX12	rs434473	17p13.1	6904934	CODING	A/G	0.60	0.40	0.96	0.76	0.24	0.16	0.0014
ALOX12	rs1126667	17p13.1	6902760	CODING	G/A	0.60	0.40	0.96	0.68	0.32	0.32	0.0095
ALOX12	rs2292350	17p13.1	6901672	INTRON	G/A	0.56	0.44	0.96	0.74	0.26	0.13	0.0012
ALOX12	rs312462	17p13.1	6913652	CODING	C/T	0.91	0.09	0.96	0.90	0.10	0.15	0
ALOX12	rs2271316	17p13.1	6915401	INTERGENIC	G/C	0.63	0.37	0.98	0.52	0.48	0.19	0.004
ALOX15	rs2664592	17p13.3	4545163	INTERGENIC	G/C	0.79	0.21	0.96	0.74	0.26	0.92	0.0002
ALOX15	rs11568131	17p13.3	4534608	UTR	C/T	0.83	0.17	0.99	0.86	0.14	0.39	0.0594
ALOX15	rs916055	17p13.3	4534834	UTR	T/C	0.66	0.34	1.00	0.61	0.39	0.95	0.0007
ALOX15	rs11078527	17p13.3	4540647	INTERGENIC	C/T	0.84	0.16	1.00	0.86	0.14	0.56	0.0014
ALOX15	rs8182325	17p13.3	4544551	INTERGENIC	C/T	0.87	0.13	0.89	0.87	0.13	0.59	0.0689
CRP	rs1130864	1q21-q23	159683091	UTR	C/T	0.69	0.31	0.86	0.63	0.37	0.53	0.0007
CRP	rs2808630	1q21-q23	159680868	INTERGENIC	T/C	0.71	0.29	0.96	0.81	0.19	0.81	0.0002
CRP	rs1205	1q21-q23	159682233	UTR	C/T	0.79	0.21	0.67	0.89	0.11	0.73	0.0002
PTGIS	rs5602	20q13.13	48121978	UTR	C/T	0.52	0.48	0.62	0.55	0.45	0.12	0
PTGIS	rs6125671	20q13.13	48175598	INTRON	C/T	0.70	0.30	0.96	0.55	0.45	0.61	0
PTGS1	rs4240474	9q32-q33.3	125145619	INTRON	G/A	0.88	0.12	0.72	0.78	0.22	0.30	0.0005
PTGS1	rs3842798	9q32-q33.3	125145743	INTRON	T/C	0.82	0.18	1.00	0.72	0.28	0.52	0.0002
PTGS1	rs4273915	9q32-q33.3	125145329	INTRON	G/C	0.84	0.16	0.96	0.75	0.25	0.68	0.0002
PTGS1	rs10306135	9q32-q33.3	125137695	INTRON	A/T	0.87	0.13	0.96	0.88	0.12	0.68	0.0007
PTGS1	rs10306194	9q32-q33.3	125157198	UTR	C/A	0.84	0.16	0.96	0.91	0.09	0.70	0
PTGS2	rs20417	1q25.2-q25.3	186650321	INTERGENIC	G/C	0.84	0.16	0.96	0.82	0.18	0.92	0.0005
PTGS2	rs5275	1q25.2-q25.3	186643058	UTR	T/C	0.65	0.35	0.93	0.70	0.30	0.94	0.0002
PTGS2	rs5277	1q25.2-q25.3	186648197	CODING	G/C	0.84	0.16	0.86	0.91	0.09	0.36	0.0005
PTGS2	rs2745557	1q25.2-q25.3	186649221	INTRON	G/A	0.83	0.17	0.96	0.90	0.10	0.01	0
PTGS2	rs689466	1q25.2-q25.3	186650751	INTERGENIC	A/G	0.82	0.18	0.96	0.68	0.32	0.36	0.0005

¹Major/minor allele reported for NHW population; minor allele frequency and Hardy-Weinberg Equilibrium (HWE) based on control population.