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. Author manuscript; available in PMC: 2016 Dec 1.
Published in final edited form as: Mol Carcinog. 2014 Oct 22;54(12):1541–1553. doi: 10.1002/mc.22228

Table 1.

Description of ALOX12, ALOX15, CRP, PTGIS, PTGS1, and PTGS2 polymorphisms, by ethnicity

Symbol SNP ID Chromosome
Location		 Coordinate Region Major/
Minor
Allele1 		non-Hispanic Whites Hispanics Proportion
Missing
Major
allele
freq.		 Minor
allele
freq.		 FDR
adjusted
HWE p
value		 Major
allele
freq.		 Minor
allele
freq.		 FDR
adjusted
HWE p
value
ALOX12 rs9904779 17p13.1 6898615 INTERGENIC G/C 0.63 0.37 0.98 0.68 0.32 0.73 0.0005
ALOX12 rs434473 17p13.1 6904934 CODING A/G 0.60 0.40 0.96 0.76 0.24 0.16 0.0014
ALOX12 rs1126667 17p13.1 6902760 CODING G/A 0.60 0.40 0.96 0.68 0.32 0.32 0.0095
ALOX12 rs2292350 17p13.1 6901672 INTRON G/A 0.56 0.44 0.96 0.74 0.26 0.13 0.0012
ALOX12 rs312462 17p13.1 6913652 CODING C/T 0.91 0.09 0.96 0.90 0.10 0.15 0
ALOX12 rs2271316 17p13.1 6915401 INTERGENIC G/C 0.63 0.37 0.98 0.52 0.48 0.19 0.004
ALOX15 rs2664592 17p13.3 4545163 INTERGENIC G/C 0.79 0.21 0.96 0.74 0.26 0.92 0.0002
ALOX15 rs11568131 17p13.3 4534608 UTR C/T 0.83 0.17 0.99 0.86 0.14 0.39 0.0594
ALOX15 rs916055 17p13.3 4534834 UTR T/C 0.66 0.34 1.00 0.61 0.39 0.95 0.0007
ALOX15 rs11078527 17p13.3 4540647 INTERGENIC C/T 0.84 0.16 1.00 0.86 0.14 0.56 0.0014
ALOX15 rs8182325 17p13.3 4544551 INTERGENIC C/T 0.87 0.13 0.89 0.87 0.13 0.59 0.0689
CRP rs1130864 1q21-q23 159683091 UTR C/T 0.69 0.31 0.86 0.63 0.37 0.53 0.0007
CRP rs2808630 1q21-q23 159680868 INTERGENIC T/C 0.71 0.29 0.96 0.81 0.19 0.81 0.0002
CRP rs1205 1q21-q23 159682233 UTR C/T 0.79 0.21 0.67 0.89 0.11 0.73 0.0002
PTGIS rs5602 20q13.13 48121978 UTR C/T 0.52 0.48 0.62 0.55 0.45 0.12 0
PTGIS rs6125671 20q13.13 48175598 INTRON C/T 0.70 0.30 0.96 0.55 0.45 0.61 0
PTGS1 rs4240474 9q32-q33.3 125145619 INTRON G/A 0.88 0.12 0.72 0.78 0.22 0.30 0.0005
PTGS1 rs3842798 9q32-q33.3 125145743 INTRON T/C 0.82 0.18 1.00 0.72 0.28 0.52 0.0002
PTGS1 rs4273915 9q32-q33.3 125145329 INTRON G/C 0.84 0.16 0.96 0.75 0.25 0.68 0.0002
PTGS1 rs10306135 9q32-q33.3 125137695 INTRON A/T 0.87 0.13 0.96 0.88 0.12 0.68 0.0007
PTGS1 rs10306194 9q32-q33.3 125157198 UTR C/A 0.84 0.16 0.96 0.91 0.09 0.70 0
PTGS2 rs20417 1q25.2-q25.3 186650321 INTERGENIC G/C 0.84 0.16 0.96 0.82 0.18 0.92 0.0005
PTGS2 rs5275 1q25.2-q25.3 186643058 UTR T/C 0.65 0.35 0.93 0.70 0.30 0.94 0.0002
PTGS2 rs5277 1q25.2-q25.3 186648197 CODING G/C 0.84 0.16 0.86 0.91 0.09 0.36 0.0005
PTGS2 rs2745557 1q25.2-q25.3 186649221 INTRON G/A 0.83 0.17 0.96 0.90 0.10 0.01 0
PTGS2 rs689466 1q25.2-q25.3 186650751 INTERGENIC A/G 0.82 0.18 0.96 0.68 0.32 0.36 0.0005
1

Major/minor allele reported for NHW population; minor allele frequency and Hardy-Weinberg Equilibrium (HWE) based on control population.