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. Author manuscript; available in PMC: 2016 Apr 1.

Published in final edited form as: Circ Cardiovasc Genet. 2014 Dec 31;8(2):389–397. doi: 10.1161/CIRCGENETICS.114.000597

Regional plots displaying the association of single nucleotide polymorphism (SNPs) at the microcephalin 1 (MCPH1) gene locus (Panel A) and at the ABO locus (Panel B), associated with circulating Angiopoietin-2 levels. The colors represent the linkage disequilibrium (expressed as r²) between neighboring SNPs. ANGPT2 indicates Angiopoietin-2. The grey horizontal line indicates the threshold of genome-wide significance (5 × 10⁻⁸).

Regional plots displaying the association of single nucleotide polymorphism (SNPs) at the microcephalin 1 (MCPH1) gene locus (Panel A) and at the ABO locus (Panel B), associated with circulating Angiopoietin-2 levels. The colors represent the linkage disequilibrium (expressed as r²) between neighboring SNPs. ANGPT2 indicates Angiopoietin-2. The grey horizontal line indicates the threshold of genome-wide significance (5 × 10⁻⁸).