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. Author manuscript; available in PMC: 2016 Apr 1.

Published in final edited form as: Circ Cardiovasc Genet. 2014 Dec 31;8(2):389–397. doi: 10.1161/CIRCGENETICS.114.000597

Regional plots displaying the association of single nucleotide polymorphisms (SNPs) at the Tie-2 (denoted as TEK) gene locus (Panel A) and the ABO locus (Panel B) with circulating Tie-2 levels. The colors represent the linkage disequilibrium (expressed as r²) between neighboring SNPs. The grey horizontal line indicates the threshold of genome-wide significance (5 × 10⁻⁸).

Regional plots displaying the association of single nucleotide polymorphisms (SNPs) at the Tie-2 (denoted as TEK) gene locus (Panel A) and the ABO locus (Panel B) with circulating Tie-2 levels. The colors represent the linkage disequilibrium (expressed as r²) between neighboring SNPs. The grey horizontal line indicates the threshold of genome-wide significance (5 × 10⁻⁸).