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. Author manuscript; available in PMC: 2016 Apr 21.
Published in final edited form as: Circulation. 2015 Feb 18;131(16):1392–1404. doi: 10.1161/CIRCULATIONAHA.114.015248

Figure 6.

Figure 6

Cardiomyocytes from remote non-infarct regions were isolated 7 days post-MI. Cells were treated with TNFα in the presence or absence of gAPN for 8 hours. gp91phox/iNOS expression (A–D), superoxide production (A/B) and peroxynitrite formation (C/D) were determined. N=5 mice/group. *P<0.05, **P<0.01 vs. TNFα alone, $$P<0.01 vs. sham. E/F: Acute administration of gAPN (intraperitoneal bolus) caused significant GLUT4 membrane translocation (E) and eNOS phosphorylation (F) in control hearts, but these responses were significantly decreased 7 days post-MI. N=6–8 animals/group. *P<0.05, **P<0.01 vs. vehicle; $P<0.05, $$P<0.01 vs. sham with the same treatment.

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