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. Author manuscript; available in PMC: 2016 Apr 28.
Published in final edited form as: FEBS Lett. 2015 Mar 18;589(10):1143–1149. doi: 10.1016/j.febslet.2015.03.010

Figure 1. Activation of canonical Wnt signaling in the retina of OIR mice.

Figure 1

Wnt signaling activation was evaluated by X-gal staining of retinal sections of normoxia control (A) or OIR (B) Axin2Lacz mice at P16. Western blot analysis of phosphorylated-LRP6 (C, D) and non-phosphorylated-β-catenin (C, E) was performed using the retinas from the OIR C57BL/6J mice and normoxia control. The expression of Vegf-a (F), a major inflammatory factor, and Gfap (G), a commonly used stress marker, at the mRNA level in the retina of OIR mice was analyzed by qRT-PCR.