Fig 6. Drug-induced perturbation experiments [5] (16 perturbations×15 gene expressions×4 time points [0, 1, 48, 72h]): (upper) raw data (middle) low-rank component and (lower) highly aberrant sparse component using threshold, where TORC1, mTOR, S6K, MEK(1), MEK(2), HER2, PI3K(α + γ, α + δ, all, β, α > β), PDK1, AKT2(1), AKT2(2), AKT1/2(1) and AKT1/2(2) represents various perturbations and HER3, pHER3, IRS-1, pAKT(308), pAKT(473), pTSC(1462), pTSC2(1571), pGSK, pPRAS, DEPTOR, pS6, p4EBP1, pPKCa, pNDRG1 and pMAPKare the measured expressions.
