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. Author manuscript; available in PMC: 2016 Apr 15.
Published in final edited form as: Int J Cardiol. 2015 Mar 5;185:198–208. doi: 10.1016/j.ijcard.2015.03.054

Figure 7. Active MMP-12 directly stimulated CD44, Caspase 3, and Caspase 8 gene expression in neutrophils.

Figure 7

(A) Neutrophils isolated from mouse blood stimulated with active MMP-12 showed increased CD44 expression compared to unstimulated cells. n=3–5/group. (B) Stimulation of isolated blood neutrophils with active MMP-12 leads to significant increase in apoptotic gene expression (Caspase 3 and Caspase 8). n=3–5/group, *p<0.05 vs. unstimulated. aMMP-12 - active MMP-12.