Fig. 5.

a Total urinary albumin excreted over 22 h. An increase in excretion was observed in the db/db groups with a trend to reduced excretion in the HBOT groups. b The albumin to creatinine ratio (ACR) is shown for all groups. A significant reduction in the ACR was observed in the Sham versus 2.4 ATA groups (p < 0.05). c Creatinine clearance data for all groups is shown. Urinary creatinine was measured by an enzyme assay, and serum creatinine was quantified by HPLC, as described in the “Materials and methods.” All db/db groups showed reduced creatinine clearance relative to Hets