Hypoxia induces protein expression of Cav1.2, Cav1.3 and HIF-1α. Expression of Cav1.2, Cav1.3, and HIF-1α protein in PC12 cells under 20 and 3 % O2 were examined by Western blot. Both Cav1.2, Cav1.3 protein (a, b), and HIF-1α protein (c, d) expression in PC12 cells was higher under 3 % O2 than that under 20 % O2. *P < 0.05; “n” stands for the number of repeated experiments