Table 4.
Multiple logistic regression analysis for the association between joint Hsp levels and COPD risk among coal workers
| Variables | All COPD | |
|---|---|---|
| n (%) | OR (95 % CI) | |
| Plasma Hsp70 and plasma Hsp27 | ||
| ᅟLow plasma Hsp70 or high plasma Hsp27 | 90 (72.6) | 1 |
| ᅟHigh plasma Hsp70 and low plasma Hsp27 | 34 (27.4) | 29.4 (9.5–91.0) |
| Plasma Hsp70 and lymphocyte Hsp27 | ||
| ᅟLow plasma Hsp70 or low lymphocyte Hsp27 | 95 (76.6) | 1 |
| ᅟHigh plasma Hsp70 and high lymphocyte Hsp27 | 29 (23.4) | 22.9 (7.2–72.6) |
| Plasma Hsp27 and lymphocyte Hsp27 | ||
| ᅟHigh plasma Hsp27 or low lymphocyte Hsp27 | 100 (80.7) | 1 |
| ᅟLow plasma Hsp27 and high lymphocyte Hsp27 | 24 (19.4) | 27.0 (6.8–106.9) |
Multiple logistic regressions were employed to analyze the associations between joint Hsp levels and risk of COPD among all the participants after adjusting for age, cumulative coal mine dust exposure, and amount of cigarette smoking; Hsp levels were categorized according to medians (plasma Hsp70, 11.2 ng/ml; lymphocyte Hsp27, 22.3 MFI; plasma Hsp27, 120.3 ng/ml)