Table IV.
Accuracy (Spike Recovery, %) and Sensitivity (LOD, LOQ) of the Related Impurities of Calcitonin Salmon and Bivalirudin
| Compounds | Spike recovery (%) | Sensitivity (μM) | |||
|---|---|---|---|---|---|
| 0.3 μM | 0.9 μM | 3.0 μM | LOD | LOQ | |
| Glu14 | 85.1 | 88.6 | 97.9 | 0.03 | 0.08 |
| AC | 113.9 | 95.1 | 100.5 | 0.04 | 0.11 |
| DG | 102.4 | 98.7 | 100.1 | 0.01 | 0.04 |
| PG | 103.4 | 98.2 | 100.1 | 0.01 | 0.04 |
| BV[12–20] | 96.1 | 103.2 | 99.8 | 0.01 | 0.03 |
| BA | 110.3 | 98.2 | 105 | 0.04 | 0.11 |
LOD limit of detection, LOQ limit of quantification, Glu 14/20 Glu14/20-calcitonin salmon, AC N-acetyl-calcitonin salmon, DG des-glycine-bivalirudin, PG plus-glycine-bivalirudin, BV[12–20] 12–20 fragment of bivalirudin, BA beta-aspartic acid-bivalirudin