Table I.

¹⁸F-FDG Kinetic Parameters Measured in Brain Regions of the Baboon Using the ¹⁸F-FDG 2-tissue Compartment Model in Control Conditions (Mean ± S.D; n = 3) and in the Presence of the P-gp Inhibitor Cyclosporine 15 mg kg⁻¹ h⁻¹ (CsA, Mean ± SD; n = 3). Student’s t Test Analysis Revealed No Difference Between Control and CsA

		K 1 (mL cm−3 min−1)	k 2 (L min−1)	k 3 (L min−1)	k 4 (L min−1)	CMRGlc (μmol/min/100 g)	V T (mL cm−3)
Brain hemispheres	Control	0.137 ± 0.031	0.263 ± 0.078	0.0485 ± 0.0037	0.0217 ± 0.0038	11.4 ± 0.9	1.73 ± 0.18
	CsA	0.113 ± 0.016	0.202 ± 0.048	0.0367 ± 0.0139	0.0174 ± 0.0108	10.8 ± 2.7	2.06 ± 0.86
Cerebellum	Control	0.164 ± 0.050	0.295 ± 0.103	0.0594 ± 0.0068	0.0233 ± 0.0053	14.9 ± 3.5	2.03 ± 0.17
	CsA	0.136 ± 0.026	0.225 ± 0.053	0.0446 ± 0.0102	0.0190 ± 0.0035	14.4 ± 3.7	2.04 ± 0.24