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. 2015 Apr 15;9(Suppl 2):S1. doi: 10.1186/1752-0509-9-S2-S1

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Copyright © 2015 Danziger et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Re-splitting Biclusters Based on BSCM. These biclusters were built on S. cerevisiae grown in batch culture and chemo stat and run through a microarray at different time points. Those conditions to the left of the dotted red line are included in the cluster and those to the right are excluded. The variance based p-value is applied to re-split the biclusters and change which conditions are included. Cluster 0005 contains 15 ribosomal genes that are expected to be co-regulated. Re-splitting increases the number of included conditions from 30/62 to 56/62. Cluster 0156 contains 31 genes related to mitosis, DNA damage, and metabolism. Re-splitting increases the number of included conditions from 32/62 to 35/62. Cluster 0229 contains 34 genes of mostly unknown function although some were related to carbohydrate metabolism. Re-splitting reduces the number of included conditions from 34/62 to 18/62.