Figure 4.

Characteristic time required for processive motors to build to stall, t_build, scaled as $\overline{\text{F}}$_max$\overline{\text{V}}$ max⁻¹K⁻¹. (A) A linear increase of t_build was observed with $\overline{\text{F}}$_max / $\overline{\text{V}}$_max, with K = 0.01 pN/nm. The values of k_off(0), k_on, and N_heads were varied from 10 s⁻¹ to 191 s⁻¹, 1 s⁻¹ to 10 s⁻¹, and 6 to 600, respectively. (B) t_build also increased linearly with 1/K. Parameter values: N_heads = 50, ρ_d(0) = 0.05 (k_on = 10 s⁻¹ and k_off(0) =191 s⁻¹). (C) Final scaling relationship for both force-dependent and force-independent motors. The same ranges of k_off(0), k_on, and N_heads as in A were used, with K ranging from 0.001 to 1 pN/nm. Each data point is from a single simulation of 200 s. To see this figure in color, go online.