Table 1.
Demographic and baseline characteristics
Measure | Placebo (n = 19) | Galantamine (n = 19) | Statistic | p |
---|---|---|---|---|
Age (mean [SD]) | 69.5 (10.3) | 62.5 (9.1) | t = 2.20 | 0.034* |
Gender (% Male) | 31.6 | 36.8 | χ2 = 0.12 | 0.732 |
Race/ethnicity (% White) | 84.2 | 78.9 | χ2 = 0.18 | 0.676 |
Marital Status (% Married) | 31.6 | 22.2 | χ2 = 2.36 | 0.308 |
Education (% with >12 years) | 42.1 | 88.9 | χ2 = 8.88 | 0.003* |
Number of prior antidepressant medications (mean [SD]) | 1.9 (1.2) | 2.6 (2.0) | t = −1.34 | 0.189 |
Baseline HDRS-24 (mean [SD])** | 30.3 (6.7) | 26.4 (4.5) | t = 2.06 | 0.047* |
Baseline MMSE (mean [SD])** | 27.4 (1.5) | 28.0 (2.0) | t = −0.88 | 0.384 |
Baseline RBANS total (mean [SD])** | 81.6 (14.6) | 90.9 (16.5) | t = −1.82 | 0.078 |
HDRS-24 = 24-item Hamilton Depression Rating Scale; MMSE = Mini-Mental Status Examination; RBANS = Repeatable Battery for Neuropsychological Status.
p < .05.
Does not include data from one subject (randomized to placebo) who did not have baseline testing; see text for details.