Overall Structure of Cg-Slx1
The GIY-YIG nuclease domain is shown in purple for β strands and yellow for the rest of the sequence. The RING domain is shown in green and the connecting scaffold helix α6 in cyan. Zinc ions are shown as gray spheres. The residues forming the active site are shown as sticks and labeled. Dotted lines indicate the loop regions, which were not observed in the electron density maps. Domain boundaries are schematically shown as rectangles on top of the panels with the residue numbers given and active site residues indicated.
See also Table S1 and Figure S2.