Table 1.

SLE diagnostic criteria (modified from [1])

Systemic lupus erythematosus: diagnostic criteria (2012 – SLICC)
Cutaneous manifestation – 4 Items	Acute Cutaneous Lupus Erythematosus/Subacute Cutaneous Lupus Erythematosus
	Chronic Cutaneous Lupus Erythematosus
	Oral ulcers
	Non-scarring alopecia
Joints – 1 Item	Synovitis > 2 peripheral joints (pain, tenderness, swelling or morning stiffness > 30 min)
Serositis – 1 item	Pleuritis, typical pleurisy ≥ 1 day, history, rub, evidence of pleural effusion, pericarditis, typical pericardial pain ≥ 1 day, EKG evidence of pericardial fusion)
Renal disorder – 1 Item	Urine protein/creatinine ratio or urinary protein concentration of 0.5 g of protein/24 h, Red blood cell casts
Haematological disorder – 3 Items	Haemolytic anaemia
	Leukopenia (<4000/mm3) or lymphopenia (<1000/mm3) separately at least once
	Thrombocytopenia (<100,000/mm3) at least once
Immunologic abnormal – 6 Items	Positive ANA
	Positive anti-dsDNA (except ELISA) on ≥ 2 occasions
	Anti-Sm
	Antiphospholipid antibody (including lupus anticoagulant, false-positive RPR, anti-cardiolipin, anti-beta2glycoprotein1)
	Low complement (C3, C4 or CH50)
	Direct Coombs test in the absence of haemolytic anaemia
Diagnosis	Fulfil 4 items (at least one clinical and one immunologic item)