Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Apr 17;14:58. doi: 10.1186/s12934-015-0234-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© Ledesma-Amaro et al.; licensee BioMed Central. 2015

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Simplified schematic representation of the de novo purine pathway in A. gossypii. Abbreviations used: ADE4 phosphoribosylpyrophosphate (PRPP) amidotransferase, ADE12 adenylosuccinate synthase, IMD3 IMP dehydrogenase, GUA1 GMP synthase and PNP1 purine nucleoside phosphorylase. The geometric shapes indicate the reactions for which the simulations using the genome-scale metabolic model iRL766 predicted an increase in the metabolic flux upon optimization of the production of biomass, guanosine and inosine (triangles, squares and pentagons, respectively).